Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007131)
Formula Reactant Enclomiphene Product Clomiphenet of N-demethylation
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007130 Enclomiphene 4-hydroxy clomiphenet Oxidation - Hydroxlyation Enclomiphene [1]
References
1 CYP2D6 is primarily responsible for the metabolism of clomiphene. Drug Metab Pharmacokinet. 2008;23(2):101-5.

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