Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007209)
Formula
SVG example
Cyclooxygenation
Reactant Dihomo-gamma-linolenic acid Product 15-HETrE
Reactant Info Product Info
Metabolic Enzyme Arachidonate 15-lipoxygenase (ALOX15) DME Info
Metabolic Type Oxidation - Cyclooxygenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007206 Gamma-linolenic acid Dihomo-gamma-linolenic acid Other reaction - Elongation Gamma-linolenic acid [1]
MR006389 Gamma-Linolenic acid Dihomo-gamma-linolenic acid Other reaction - Elongation Omega-6-FA [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007207 Dihomo-gamma-linolenic acid Arachidonic Acid Other reaction - Delta-5-desaturation Gamma-linolenic acid [1]
MR007210 Dihomo-gamma-linolenic acid Prostaglandin E1 Unclear Gamma-linolenic acid [1]
MR006390 Dihomo-gamma-linolenic acid Arachidonic acid Multi-steps Reaction - Elongation; desaturation Omega-6-FA [2]
References
1 Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes
2 Health implications of high dietary omega-6 polyunsaturated Fatty acids. J Nutr Metab. 2012;2012:539426.

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