Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007210)
Formula
PTGS1 ...
SVG example
Reactant Dihomo-gamma-linolenic acid Product Prostaglandin E1
Reactant Info Product Info
Metabolic Enzyme Prostaglandin G/H synthase 1 (COX-1) DME Info
Prostaglandin G/H synthase 2 (COX-2) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007206 Gamma-linolenic acid Dihomo-gamma-linolenic acid Other reaction - Elongation Gamma-linolenic acid [1]
MR006389 Gamma-Linolenic acid Dihomo-gamma-linolenic acid Other reaction - Elongation Omega-6-FA [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007209 Dihomo-gamma-linolenic acid 15-HETrE Oxidation - Cyclooxygenation Gamma-linolenic acid [1]
MR007207 Dihomo-gamma-linolenic acid Arachidonic Acid Other reaction - Delta-5-desaturation Gamma-linolenic acid [1]
MR006390 Dihomo-gamma-linolenic acid Arachidonic acid Multi-steps Reaction - Elongation; desaturation Omega-6-FA [2]
References
1 Gamma-linolenic acid, Dihommo-gamma linolenic, Eicosanoids and Inflammatory Processes
2 Health implications of high dietary omega-6 polyunsaturated Fatty acids. J Nutr Metab. 2012;2012:539426.

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