Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007642)
Formula Reactant Nomifensine Product Nomifensine N-oxides(H7 and H8)
Reactant Info Product Info
Metabolic Enzyme Dimethylaniline oxidase 3 (FMO3) DME Info
Dimethylaniline oxidase 1 (FMO1) DME Info
Dimethylaniline oxidase 5 (FMO5) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007636 Nomifensine Nomifensinc N-hydroxylamine (H6) Unclear Nomifensine [1]
MR007640 Nomifensine Nomifensine H1 Unclear Nomifensine [1]
MR007643 Nomifensine Nomifensine H2 Unclear Nomifensine [1]
MR007638 Nomifensine Nomifensine H4 Unclear Nomifensine [1]
References
1 In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism

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