Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007640)
Formula Reactant Nomifensine Product Nomifensine H1
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007636 Nomifensine Nomifensinc N-hydroxylamine (H6) Unclear Nomifensine [1]
MR007643 Nomifensine Nomifensine H2 Unclear Nomifensine [1]
MR007638 Nomifensine Nomifensine H4 Unclear Nomifensine [1]
MR007642 Nomifensine Nomifensine N-oxides(H7 and H8) Unclear Nomifensine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007641 Nomifensine H1 Nomifensine M7,M8,M9 Unclear Nomifensine [1]
References
1 In vitro metabolism studies of nomifensine monooxygenation pathways: metabolite identification, reaction phenotyping, and bioactivation mechanism

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