Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008112)
Formula
SVG example
Unclear
Reactant Penicillin V Product 6-aminopenicillanic acid
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008109 Penicillin V Penicilloic acid Hydrolysis - Hydrolysis Penicillin V [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008098 Cyclacillin 6-APA Hydrolysis - Hydrolysis Cyclacillin [3]
MR008130 Penicillin 6-aminopenicillanic acid Unclear - Unclear Penicillin [4], [5]
MR001971 Penicillin G 6-aminopenicillanic acid Unclear Penicillin G [6]
MR008106 Penicillin G Sodium 6-aminopenicillanic acid Hydrolysis - Hydrolysis Penicillin G Sodium [4]
References
1 Enzyme-catalyzed biodegradation of penicillin fermentation residues by -lactamase OtLac from Ochrobactrum tritici
2 Isolation and Characterization of Ochrobactrum tritici for Penicillin V Potassium Degradation
3 Sex- and species-related nephropathy of 6-(1-aminocyclohexanecarboxamido)penicillanic acid (cyclacillin) and its relationship to the metabolic disposition of the drug
4 Metabolism of penicillins to penicilloic acids and 6-aminopenicillanic acid in man and its significance in assessing penicillin absorption
5 Ligand-induced conformational change in penicillin acylase
6 McEvoy, G.K. (ed.). American Hospital Formulary Service - Drug Information 1999. Bethesda, MD:American Society of Health-System Pharmacists, Inc. 1999 (Plus Supplements)., p. 1760

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