Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008660)
Formula
CYP3A4 ...
SVG example
Unclear
Reactant (E)-4-OH-CLOM Product (E)-4-OH-DE-CLOM
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 2C8 (CYP2C8) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008659 Clomiphene citrate (E)-4-OH-CLOM Unclear - Unclear Clomiphene citrate [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008658 (E)-DE-CLOM (E)-4-OH-DE-CLOM Unclear - Unclear Clomiphene citrate [1]
References
1 Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolites

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