Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008731)
Formula
SVG example
N-demethylation
Reactant Arbidol Product Arbidol M3-2 metabolite
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - N-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008727 Arbidol Arbidol M1 metabolite Oxidation - Dealkylation Arbidol [1]
MR008748 Arbidol Arbidol M10 metabolite Conjugation - Sulfate conjugation Arbidol [1]
MR008749 Arbidol Arbidol M18 metabolite Conjugation - O-glucuronidation Arbidol [1]
MR008746 Arbidol Arbidol M3-1 metabolite Multi-steps Reaction - Sulfate conjugation; sulfoxidation Arbidol [1]
MR008734 Arbidol Arbidol M5 metabolite Multi-steps Reaction - N-demethylation; sulfoxidation Arbidol [1]
MR008737 Arbidol Arbidol M6-1 metabolite Oxidation - Sulfoxidation Arbidol [1]
MR008750 Arbidol Arbidol M6-2 metabolite Oxidation - Hydroxylation Arbidol [1]
MR008740 Arbidol Arbidol M7 metabolite Multi-steps Reaction - N-demethylation; sulfoxidation Arbidol [1]
MR008743 Arbidol Arbidol M8 metabolite Oxidation - Sulfoxidation Arbidol [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008733 Arbidol M3-2 metabolite Arbidol M17-2 metabolite Conjugation - O-glucuronidation Arbidol [2]
MR008732 Arbidol M3-2 metabolite Arbidol M9-2 metabolite Conjugation - Sulfate conjugation Arbidol [2]
References
1 Pharmacokinetics, metabolism, and excretion of the antiviral drug arbidol in humans
2 DrugBank(Pharmacology-Metabolism):Arbidol

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