Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR008834)
Formula
SVG example
O-dealkylation
Reactant Umeclidinium Product Umeclidinium M14
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - O-dealkylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008832 Umeclidinium Umeclidinium M33 Oxidation - Hydroxylation Umeclidinium [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013194 Umeclidinium bromide Umeclidinium M14 Oxidation - O-dealkylation Umeclidinium bromide [2]
References
1 DrugBank(Pharmacology-Metabolism):Umeclidinium
2 CLINICAL PHARMACOLOGY AND BIOPHARMACEUTICS REVIEW: Umeclidinium Bromide

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