Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009011)
Formula
SVG example
Unclear
Reactant Clomipramine Product Clomipramine N-oxide
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009013 Clomipramine 10-OH-clomipramine Oxidation - Aliphatic hydroxylation Clomipramine [1]
MR009001 Clomipramine 2-hydroxyclomipramine Oxidation - 2-hydroxylation Clomipramine [1]
MR009005 Clomipramine 8-hydroxyclomipramine Oxidation - 8-hydroxylation Clomipramine [1]
MR009012 Clomipramine 8-OH-clomipramine Oxidation - Aromatic hydroxylation Clomipramine [1]
MR009009 Clomipramine Desmethylclomipramine Oxidation - N-demethylation Clomipramine [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR006578 Clomipramine hydrochloride Clomipramine N-oxide Oxidation - Oxidationn Clomipramine hydrochloride [2]
References
1 Pharmacogenomics knowledge for personalized medicine Clin Pharmacol Ther. 2012 Oct;92(4):414-7. doi: 10.1038/clpt.2012.96.
2 Metabolism of clomipramine in a Japanese psychiatric population: hydroxylation, desmethylation, and glucuronidation

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