Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009416)
Formula
CYP1A1 ...
SVG example
Sulfoxidation
Reactant Almokalant Product Almokalant Metabolite M13
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A1 (CYP1A1) DME Info
Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2B6 (CYP2B6) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Sulfoxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009417 Almokalant Almokalant Metabolite M16 Unclear - Unclear Almokalant [1]
MR009415 Almokalant Almokalant Metabolite M17 Oxidation - Deethylation Almokalant [1]
MR009420 Almokalant Almokalant Metabolite M18 Unclear - Unclear Almokalant [1]
MR009419 Almokalant Almokalant Metabolite M3 Unclear - Unclear Almokalant [1]
MR009418 Almokalant Almokalant Metabolite M6 Oxidation - Dealkylation Almokalant [1]
References
1 An assessment of human liver-derived in vitro systems to predict the in vivo metabolism and clearance of almokalant

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