Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009550)
Formula
CYP3A5 ...
SVG example
N-demethylation
Reactant Ritonavir Product N-Desmethylritonavir
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A5 (CYP3A5) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - N-demethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009551 Ritonavir Ritonavir metabolite M1 Unclear - Unclear Ritonavir [1]
MR009552 Ritonavir Ritonavir metabolite M11 Unclear - Unclear Ritonavir [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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