Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009584)
Formula
SVG example
Sulfonation
Reactant Para-Hydroxyrosiglitazone Product Para-O-Sulfate rosiglitazone
Reactant Info Product Info
Metabolic Type Oxidation - Sulfonation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009582 Rosiglitazone Para-Hydroxyrosiglitazone Oxidation - Hydroxylation Rosiglitazone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009583 Para-Hydroxyrosiglitazone N-Desmethyl-para-hydroxy rosiglitazone Oxidation - N-demethylation Rosiglitazone [1]
MR009585 Para-Hydroxyrosiglitazone Para-O-Glucuronide rosiglitazone Conjugation - Glucuronidation Rosiglitazone [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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