Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009585)
Formula Reactant Para-Hydroxyrosiglitazone Product Para-O-Glucuronide rosiglitazone
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009582 Rosiglitazone Para-Hydroxyrosiglitazone Oxidation - Hydroxylation Rosiglitazone [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009583 Para-Hydroxyrosiglitazone N-Desmethyl-para-hydroxy rosiglitazone Oxidation - N-demethylation Rosiglitazone [1]
MR009584 Para-Hydroxyrosiglitazone Para-O-Sulfate rosiglitazone Oxidation - Sulfonation Rosiglitazone [1]
References
1 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.

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