Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009625)
Formula
SVG example
Glucuronidation
Reactant 5alpha-dihydrotestosterone Product 3-alpha-Androstanediol glucuronide
Reactant Info Product Info
Metabolic Type Conjugation - Glucuronidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012850 Androstenedione 5alpha-dihydrotestosterone Unclear Androstenedione [1]
MR003306 Androstanedione 5alpha-dihydrotestosterone Unclear BRN-2217626 [2]
MR004907 Dihydrotestosterone undecanoate 5alpha-dihydrotestosterone Unclear Testosterone undecanoate [3]
MR004535 Testosterone 5alpha-dihydrotestosterone Unclear AC-12166 [4]
MR004894 Testosterone 5alpha-dihydrotestosterone Unclear Testosterone cypionate [5]
MR004901 Testosterone 5alpha-dihydrotestosterone Unclear Testosterone undecanoate [3]
MR009624 Testosterone 5alpha-dihydrotestosterone Unclear - Unclear Testosterone enanthate [6]
MR009028 Testosterone 5alpha-dihydrotestosterone Unclear - Unclear EPIANDROSTERONE [7]
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Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004902 5alpha-dihydrotestosterone 3-alpha-androstanediol Unclear Testosterone undecanoate [8]
MR004904 5alpha-dihydrotestosterone 3-beta-androstenediol Unclear Testosterone undecanoate [8]
MR004895 5alpha-dihydrotestosterone 3alpha-Androstanediol glucuronide Unclear Testosterone cypionate [9]
MR004536 5alpha-dihydrotestosterone Androstanediol Unclear AC-12166 [4]
MR009029 5alpha-dihydrotestosterone 5alpha-androstane-3beta,17beta-diol(3beta,17beta-AAD) Reduction - 17beta-hydroxysteroid oxido-reduction EPIANDROSTERONE [7]
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Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR004903 3-alpha-androstanediol 3-alpha-androstanediol glucuronide Unclear Testosterone undecanoate [8]
References
1 Androstenedione (a Natural Steroid and a Drug Supplement): A Comprehensive Review of Its Consumption, Metabolism, Health Effects, and Toxicity with Sex Differences
2 Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans Trends Endocrinol Metab. 2003 Dec;14(10):473-9. doi: 10.1016/j.tem.2003.10.005.
3 Importance of measuring testosterone in enzyme-inhibited plasma for oral testosterone undecanoate androgen replacement therapy clinical trials
4 Preliminary observations on steroid metabolism in isolated epithelum of guinea pig seminal vesicle
5 The history of synthetic testosterone
6 DrugBank(Pharmacology-Metabolism):Testosterone enanthate
7 Oxidative metabolism of dehydroepiandrosterone (DHEA) and biologically active oxygenated metabolites of DHEA and epiandrosterone (EpiA)--recent reports
8 Metabolism of dihydrotestosterone in human liver: importance of 3alpha- and 3beta-hydroxysteroid dehydrogenase
9 DrugBank(Pharmacology-Metabolism):Testosterone cypionate

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