Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009781)
Formula
CYP3A4 ...
SVG example
Hydroxylation
Reactant 17-DMAG M2 Product 17-DMAG M6
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Cytochrome P450 2C8 (CYP2C8) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009779 Alvespimycin hydrochloride 17-DMAG M2 Oxidation - Hydroxylation Alvespimycin hydrochloride [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009780 17-DMAG M2 17-DMAG M5 Unclear - Unclear Alvespimycin hydrochloride [1]
References
1 In vitro metabolism of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin in human liver microsomes

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