Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009795)
Formula
SVG example
Unclear
Reactant AST-1306 Product Allitinib M14
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009785 AST-1306 Allitinib M1 Oxidation - O-dealkylation AST-1306 [1]
MR009797 AST-1306 Allitinib M10 Unclear - Unclear AST-1306 [1]
MR009799 AST-1306 Allitinib M2 Unclear - Unclear AST-1306 [1]
MR009792 AST-1306 Allitinib M6 Unclear - Unclear AST-1306 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009782 Alvespimycin hydrochloride 17-DMAG M1 Oxidation - Hydroxylation Alvespimycin hydrochloride [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009796 Allitinib M14 Allitinib M16 Unclear - Unclear AST-1306 [1]
References
1 Metabolism and pharmacokinetics of allitinib in cancer patients: the roles of cytochrome P450s and epoxide hydrolase in its biotransformation
2 In vitro metabolism of 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin in human liver microsomes

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