Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009797)
Formula
CYP1A2 ...
SVG example
Unclear
Reactant AST-1306 Product Allitinib M10
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009785 AST-1306 Allitinib M1 Oxidation - O-dealkylation AST-1306 [1]
MR009795 AST-1306 Allitinib M14 Unclear - Unclear AST-1306 [1]
MR009799 AST-1306 Allitinib M2 Unclear - Unclear AST-1306 [1]
MR009792 AST-1306 Allitinib M6 Unclear - Unclear AST-1306 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009798 Allitinib M10 Allitinib M5 Oxidation - O-dealkylation AST-1306 [1]
References
1 Metabolism and pharmacokinetics of allitinib in cancer patients: the roles of cytochrome P450s and epoxide hydrolase in its biotransformation

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