Details of the Metabolic Reaction (MR)
General Information of This Metabolic Reaction (MR) (ID: MR009840) | ||||||
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Formula | Reactant | Alpelisib | Product | Alpelisib Metabolite M1 | ||
Reactant Info | Product Info | |||||
Metabolic Type | Multi-steps Reaction - Glucuronidation; oxidation | |||||
Other MR(s) Related to The Reactant of This MR | |||||||||||||||||||||||||||||||||||||||||||||||||||||
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Other MR(s) That Metabolize The Reactant of This MR | |||||||||||||||||||||||||||||||||||||||||||||||||||||
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References | ||||||
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1 | Absorption, distribution, metabolism, and excretion of [(14)C]BYL719 (alpelisib) in healthy male volunteers. Cancer Chemother Pharmacol. 2015 Oct;76(4):751-60. |
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