Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009993)
Formula Reactant Methadone Product 4-dimethylamino-22-diphenylvaleric acid
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009998 Methadone EDDP Oxidation - N-demethylation Methadone [1], [2]
MR009996 Methadone Methadol Unclear - Unclear Methadone [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009994 4-dimethylamino-22-diphenylvaleric acid 4-methylamino-2,2-diphenylvaleric acid Unclear - Unclear Methadone [1], [2]
References
1 Methadone metabolism and drug-drug interactions: in vitro and in vivo literature review. J Pharm Sci. 2018 Dec;107(12):2983-2991.
2 Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics

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