Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR009996)
Formula
ADH
SVG example
Unclear
Reactant Methadone Product Methadol
Reactant Info Product Info
Metabolic Enzyme Alcohol dehydrogenase (ADH) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009993 Methadone 4-dimethylamino-22-diphenylvaleric acid Unclear - Unclear Methadone [1], [2]
MR009998 Methadone EDDP Oxidation - N-demethylation Methadone [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR009997 Methadol Normethadol Unclear - Unclear Methadone [1], [2]
References
1 Methadone metabolism and drug-drug interactions: in vitro and in vivo literature review. J Pharm Sci. 2018 Dec;107(12):2983-2991.
2 Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics

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