Details of the Metabolic Reaction (MR)
| General Information of This Metabolic Reaction (MR) (ID: MR010187) | ||||||
|---|---|---|---|---|---|---|
| Formula | Reactant | Savolitinib | Product | Savolitinib Metabolite M5 | ||
| Reactant Info | Product Info | |||||
| Metabolic Enzyme | Cytochrome P450 3A4 (CYP3A4) | DME Info | ||||
| Metabolic Type | Unclear - Unclear | |||||
| Other MR(s) Related to The Reactant of This MR | |||||||||||||||||||||||||||||||||||||||||||||||
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| Other MR(s) That Metabolize The Reactant of This MR | |||||||||||||||||||||||||||||||||||||||||||||||
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| Other MR(s) Related to The Product of This MR | |||||||||||||||||||||||||||||
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| Other MR(s) That Metabolize The Produtc of This MR | |||||||||||||||||||||||||||||
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| References | ||||||
|---|---|---|---|---|---|---|
| 1 | A Phase 1 Study to Evaluate Absolute Bioavailability and Absorption, Distribution, Metabolism, and Excretion of Savolitinib in Healthy Male Volunteers | |||||
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