Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010185)
Formula
CYP1A2 ...
SVG example
Unclear
Reactant Savolitinib Product Savolitinib Metabolite M2
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 1A2 (CYP1A2) DME Info
Mephenytoin 4-hydroxylase (CYP2C19) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010189 Savolitinib Savolitinib Metabolite M17 Unclear - Unclear Savolitinib [1]
MR010183 Savolitinib Savolitinib Metabolite M3 Unclear - Unclear Savolitinib [1]
MR010190 Savolitinib Savolitinib Metabolite M38 Unclear - Unclear Savolitinib [1]
MR010187 Savolitinib Savolitinib Metabolite M5 Unclear - Unclear Savolitinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010186 Savolitinib Metabolite M2 Savolitinib Metabolite M8 Unclear - Unclear Savolitinib [1]
References
1 A Phase 1 Study to Evaluate Absolute Bioavailability and Absorption, Distribution, Metabolism, and Excretion of Savolitinib in Healthy Male Volunteers

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