Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010219)
Formula
SVG example
Unclear
Reactant Taxol Product p-3-hydroxypaclitaxel
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010220 Taxol 6alpha,3'p-dihydroxypaxlitaxel Unclear - Unclear Taxol [1]
MR011040 Taxol 6alpha-hydroxypaclitaxel Unclear - Unclear Taxol [2]
MR010218 Taxol 6alpha-hydroxypaclitaxel?(6alpha-OHP) Unclear - Unclear Taxol [2]
MR011041 Taxol p-3'-hydroxypaclitaxel Unclear - Unclear Taxol [2]
References
1 Metabolism of paclitaxel in mice
2 The Quantification of Paclitaxel and Its Two Major Metabolites in Biological Samples by HPLC-MS/MS and Its Application in a Pharmacokinetic and Tumor Distribution Study in Xenograft Nude Mouse

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