General Information of This Metabolic Reaction (MR) (ID:
MR011041) |
Formula |
|
Reactant |
Taxol |
Product |
p-3'-hydroxypaclitaxel |
Reactant Info
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Product Info
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Metabolic Enzyme
|
Cytochrome P450 3A4 (CYP3A4)
|
DME Info
|
Metabolic Type
|
Unclear
-
Unclear
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Other MR(s) Related to The Reactant of This MR |
Other MR(s) That Metabolize The Reactant of This MR
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References |
1 |
Metabolism of paclitaxel in mice
|
2 |
The Quantification of Paclitaxel and Its Two Major Metabolites in Biological Samples by HPLC-MS/MS and Its Application in a Pharmacokinetic and Tumor Distribution Study in Xenograft Nude Mouse
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