Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010389)
Formula
CYP3A4 ...
SVG example
N-desmethylation
Reactant VX-680 Product VRT-171335
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C8 (CYP2C8) DME Info
Metabolic Type Oxidation - N-desmethylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010388 VX-680 VRT-7500074 Oxidation - N-oxidation VX-680 [1]
References
1 Effect of human flavin-containing monooxygenase 3 polymorphism on the metabolism of aurora kinase inhibitors

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