Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR010499)
Formula
SVG example
Oxidative Deamination
Reactant Emixustat Product ACU-5116
Reactant Info Product Info
Metabolic Type Oxidation - Oxidative Deamination
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010506 Emixustat ACU-4861 Oxidation - Hydroxylation Emixustat [1], [2]
MR010507 Emixustat ACU-4949 Oxidation - Hydroxylation Emixustat [1], [2]
MR010508 Emixustat ACU-4982 Oxidation - Hydroxylation Emixustat [1], [2]
MR010510 Emixustat Emixustat Metabolite M11 Multi-steps Reaction - Hydroxylation; Dehydrogenation Emixustat [1], [2]
MR010509 Emixustat Emixustat Metabolite M20 Oxidation - Hydroxylation Emixustat [1], [2]
MR010505 Emixustat Emixustat Metabolite M3 Multi-steps Reaction - Hydroxylation; Glucuronidation Emixustat [1], [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR010500 ACU-5116 ACU-5124 Oxidation - Hydroxylation Emixustat [1], [2]
MR010502 ACU-5116 ACU-5144 Oxidation - Hydroxylation Emixustat [1], [2]
MR010503 ACU-5116 ACU-5145 Oxidation - Hydroxylation Emixustat [1], [2]
MR010501 ACU-5116 ACU-5149 Oxidation - Hydroxylation Emixustat [1], [2]
MR010504 ACU-5116 ACU-5188 Oxidation - Dehydrogenation Hydroxylation Emixustat [1], [2]
References
1 Oxidative Deamination of Emixustat by Human Vascular Adhesion Protein-1/Semicarbazide-Sensitive Amine Oxidase
2 Disposition, profiling and identification of emixustat and its metabolites in humans

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