Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011133)
Formula
CYP2D6 ...
SVG example
Hydroxylation
Reactant Pitolisant Product BP2.941
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011135 Pitolisant BP1.8054 Unclear - Unclear Pitolisant [1]
MR011134 Pitolisant BP2.951 Conjugation - Glycine conjugation Pitolisant [2]
References
1 FDA Center for Drug Evaluation and Research: Pitolisant Non-clinical Review(s)
2 Wakix, INN-Pitolisant - European Medicines Agency - Europa EU

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