Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011423)
Formula
CYP
SVG example
Glutathione conjugation
Reactant TAS-120 Product TAS-120 Metabolite F18
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 (CYP) DME Info
Metabolic Type Conjugation - Glutathione conjugation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011427 TAS-120 Desmethyl futibatinib Unclear - Unclear TAS-120 [1]
MR011438 TAS-120 Monohydroxy futibatinib Unclear - Unclear TAS-120 [1]
MR011434 TAS-120 Possible intermediate metabolite Oxidation - Oxidation TAS-120 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011424 TAS-120 Metabolite F18 TAS-120 Metabolite P7 Unclear - Unclear TAS-120 [1]
References
1 Evaluation of the Mass Balance and Metabolic Profile of Futibatinib in Healthy Participants

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