Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011427)
Formula
SVG example
Unclear
Reactant TAS-120 Product Desmethyl futibatinib
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011438 TAS-120 Monohydroxy futibatinib Unclear - Unclear TAS-120 [1]
MR011434 TAS-120 Possible intermediate metabolite Oxidation - Oxidation TAS-120 [1]
MR011423 TAS-120 TAS-120 Metabolite F18 Conjugation - Glutathione conjugation TAS-120 [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011430 Desmethyl futibatinib Glucuronide of Desmethyl futibatinib Conjugation - Glucuronidation TAS-120 [1]
MR011428 Desmethyl futibatinib Reduction of Desmethyl futibatinib Unclear - Unclear TAS-120 [1]
MR011429 Desmethyl futibatinib Sulfate Desmethyl futibatinib Conjugation - Sulfation TAS-120 [1]
References
1 Evaluation of the Mass Balance and Metabolic Profile of Futibatinib in Healthy Participants

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