Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR011594)
Formula Reactant Bexagliflozin Product EGT0001301
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C8 (CYP2C8) DME Info
Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Oxidation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011596 Bexagliflozin EGT0001663 Unclear - Unclear Bexagliflozin [1]
MR011599 Bexagliflozin EGT0002147 Unclear - Unclear Bexagliflozin [1]
MR011598 Bexagliflozin EGT0002148 Unclear - Unclear Bexagliflozin [1]
MR011597 Bexagliflozin EGT0002149 Conjugation - O-glucuronidation Bexagliflozin [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011595 EGT0001301 EGT0001494 Oxidation - Oxidation Bexagliflozin [1]
References
1 Metabolism and disposition of the SGLT2 inhibitor bexagliflozin in rats, monkeys and humans

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