General Information of This Metabolic Reaction (MR) (ID: MR011607)
Formula Reactant Tivantinib Product Tivantinib Metabolite M5
Reactant Info Product Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011610 Tivantinib Tivantinib Metabolite M10 Oxidation - Oxidation Tivantinib [1]
MR011603 Tivantinib Tivantinib Metabolite M4 Unclear - Unclear Tivantinib [1]
MR011600 Tivantinib Tivantinib Metabolite M8 precursor Unclear - Unclear Tivantinib [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR011609 Tivantinib Metabolite M5 Tivantinib Metabolite M12 Oxidation - Oxidation Tivantinib [1]
MR011608 Tivantinib Metabolite M5 Tivantinib Metabolite M15,16 Unclear - Unclear Tivantinib [1]
References
1 Stereoselective hydroxylation by CYP2C19 and oxidation by ADH4 in the in vitro metabolism of tivantinib

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