Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR012964)
Formula Reactant Idelalisib Product Idelalisib Metabolite M2
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C9 (CYP2C9) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012969 Idelalisib GS-563117 Unclear Idelalisib [1], [2]
MR012981 Idelalisib Idelalisib Metabolite M10 Unclear Idelalisib [2]
MR012982 Idelalisib Idelalisib Metabolite M11 Unclear Idelalisib [2]
MR012983 Idelalisib Idelalisib Metabolite M12 Unclear Idelalisib [2]
MR012984 Idelalisib Idelalisib Metabolite M13 Unclear Idelalisib [2]
MR012985 Idelalisib Idelalisib Metabolite M14 Unclear Idelalisib [2]
MR012978 Idelalisib Idelalisib Metabolite M5 Unclear Idelalisib [2]
MR012979 Idelalisib Idelalisib Metabolite M8 Unclear Idelalisib [2]
MR012980 Idelalisib Idelalisib Metabolite M9 Unclear Idelalisib [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012977 Idelalisib Metabolite M2 Idelalisib Metabolite M4 Unclear Idelalisib [2]
MR012965 Idelalisib Metabolite M2 Idelalisib Metabolite M6 Unclear Idelalisib [2]
References
1 Clinical drug interaction profile of idelalisib in healthy subjects
2 Identification of Novel Pathways in Idelalisib Metabolism and Bioactivation

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