Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013189)
Formula
SVG example
Hydroxylation
Reactant Umeclidinium bromide Product Umeclidinium M33
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013194 Umeclidinium bromide Umeclidinium M14 Oxidation - O-dealkylation Umeclidinium bromide [1]
MR013195 Umeclidinium bromide Umeclidinium M37 Oxidation - Hydroxylation Umeclidinium bromide [1]
MR013192 Umeclidinium bromide Umeclidinium M51 Unclear Umeclidinium bromide [1]
MR013196 Umeclidinium bromide Umeclidinium M61 Unclear Umeclidinium bromide [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008832 Umeclidinium Umeclidinium M33 Oxidation - Hydroxylation Umeclidinium [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR008833 Umeclidinium M33 Umeclidinium M21 Conjugation - Glucuronidation Umeclidinium [2]
MR013191 Umeclidinium M33 Umeclidinium M21 Conjugation - Glucuronidation Umeclidinium bromide [1]
MR013190 Umeclidinium M33 Umeclidinium M34 Oxidation - Methylation Umeclidinium bromide [1]
References
1 CLINICAL PHARMACOLOGY AND BIOPHARMACEUTICS REVIEW: Umeclidinium Bromide
2 DrugBank(Pharmacology-Metabolism):Umeclidinium

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.