Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013361)
Formula Reactant Hydroxyperospirone Product M-813 Metabolite MX6
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013355 M-813 Hydroxyperospirone Oxidation - Hydrolyzationn M-813 [1], [2]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013356 Hydroxyperospirone M-813 Metabolite MX11 Unclear M-813 [2], [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013367 ID-15010 M-813 Metabolite MX6 Unclear M-813 [2]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013362 M-813 Metabolite MX6 M-813 Metabolite MX9 Unclear M-813 [3]
References
1 Steady-state pharmacokinetics of a new antipsychotic agent perospirone and its active metabolite, and its relationship with prolactin response. Ther Drug Monit. 2004 Aug;26(4):361-5.
2 The wide variability of perospirone metabolism and the effect of perospirone on prolactin in psychiatric patients
3 In vitro metabolism of perospirone in rat, monkey and human liver microsomes

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.