Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013355)
Formula
CYP2C8 ...
SVG example
Hydrolyzationn
Reactant M-813 Product Hydroxyperospirone
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2C8 (CYP2C8) DME Info
Cytochrome P450 1A1 (CYP1A1) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Metabolic Type Oxidation - Hydrolyzationn
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013365 M-813 ID-11614 Unclear M-813 [1]
MR013368 M-813 ID-11926 Unclear M-813 [1]
MR013366 M-813 ID-15010 Unclear M-813 [1]
MR013363 M-813 M-813 Metabolite MX1 Unclear M-813 [2], [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013356 Hydroxyperospirone M-813 Metabolite MX11 Unclear M-813 [1], [2]
MR013361 Hydroxyperospirone M-813 Metabolite MX6 Unclear M-813 [2]
References
1 The wide variability of perospirone metabolism and the effect of perospirone on prolactin in psychiatric patients
2 In vitro metabolism of perospirone in rat, monkey and human liver microsomes

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