Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013440)
Formula
CYP2D6 ...
SVG example
Aromatic hydroxylation
Reactant Maprotiline hydrochloride Product 2-OH-maprotiline
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 2D6 (CYP2D6) DME Info
Cytochrome P450 1A1 (CYP1A1) DME Info
Metabolic Type Oxidation - Aromatic hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013439 Maprotiline hydrochloride 3-OH-maprotiline Oxidation - Aromatic hydroxylation Maprotiline hydrochloride [1]
MR013438 Maprotiline hydrochloride Desmethylmaprotiline Oxidation - N-demethylation Maprotiline hydrochloride [1]
References
1 Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development. Curr Med Chem. 2009;16(31):4066-218.

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