Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013675)
Formula
SVG example
12-OH-dehydrogenation
Reactant Deoxycholic acid Product 12-keto-DCA
Reactant Info Product Info
Metabolic Type Oxidation - 12-OH-dehydrogenation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013670 Deoxycholic acid 15beta-hydroxy-DCA Oxidation - 15-hydroxylation Deoxycholic acid [1]
MR013673 Deoxycholic acid 1beta-OH-DCA Unclear Deoxycholic acid [2]
MR013674 Deoxycholic acid 3-keto-DCA Oxidation - 3-OH-dehydrogenation Deoxycholic acid [1]
MR013677 Deoxycholic acid CA Oxidation - 7-hydroxylation Deoxycholic acid [1]
MR013672 Deoxycholic acid Taurocholic acid Unclear Deoxycholic acid [3]
MR013676 Deoxycholic acid UCA Oxidation - 7-hydroxylation Deoxycholic acid [1]
References
1 Deoxycholic acid transformations catalyzed by selected filamentous fungi
2 CYP3A Specifically Catalyzes 1-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity
3 Increased sulfation and decreased 7alpha-hydroxylation of deoxycholic acid in ethinyl estradiol-induced cholestasis in rats

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