Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013673)
Formula
CYP46A1 ...
SVG example
Reactant Deoxycholic acid Product 1beta-OH-DCA
Reactant Info Product Info
Metabolic Enzyme Cholesterol 24-hydroxylase (CYP46A1) DME Info
Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 3A5 (CYP3A5) DME Info
Cytochrome P450 3A7 (CYP3A7) DME Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013675 Deoxycholic acid 12-keto-DCA Oxidation - 12-OH-dehydrogenation Deoxycholic acid [1]
MR013670 Deoxycholic acid 15beta-hydroxy-DCA Oxidation - 15-hydroxylation Deoxycholic acid [1]
MR013674 Deoxycholic acid 3-keto-DCA Oxidation - 3-OH-dehydrogenation Deoxycholic acid [1]
MR013677 Deoxycholic acid CA Oxidation - 7-hydroxylation Deoxycholic acid [1]
MR013672 Deoxycholic acid Taurocholic acid Unclear Deoxycholic acid [2]
MR013676 Deoxycholic acid UCA Oxidation - 7-hydroxylation Deoxycholic acid [1]
References
1 Deoxycholic acid transformations catalyzed by selected filamentous fungi
2 Increased sulfation and decreased 7alpha-hydroxylation of deoxycholic acid in ethinyl estradiol-induced cholestasis in rats

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