Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013681)
Formula
CYP3A4 ...
SVG example
Hydroxylation
Reactant Enzalutamide Product Enzalutamide metabolite M6 enzalutamide
Reactant Info Product Info
Metabolic Enzyme Cytochrome P450 3A4 (CYP3A4) DME Info
Cytochrome P450 2C8 (CYP2C8) DME Info
Metabolic Type Oxidation - Hydroxylation
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013682 Enzalutamide metabolite M6 enzalutamide N-desmethyl enzalutamide Oxidation - Demethylation Enzalutamide [1]
References
1 Absorption, Distribution, Metabolism, and Excretion of the Androgen Receptor Inhibitor Enzalutamide in Rats and Dogs

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