Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013703)
Formula
SVG example
Reactant BIA 9-1106 Product BIA 9-1101
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013702 Opicapone BIA 9-1106 Conjugation - Glucuronidation Opicapone [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR013707 Opicapone BIA 9-1101 Multi-steps Reaction - Methylation; reduction Opicapone [1]
MR013701 BIA 9-1079 BIA 9-1101 Oxidation - 3\O\methylation Opicapone [2]
References
1 Pharmacokinetics, pharmacodynamics and tolerability of opicapone, a novel catechol-O-methyltransferase inhibitor, in healthy subjects: prediction of slow enzyme-inhibitor complex dissociation of a short-living and very long-acting inhibitor
2 Metabolism and disposition of opicapone in the rat and metabolic enzymes phenotyping

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