Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR013769)
Formula
SVG example
Unclear
Reactant Beta-Hydroxyphenylbutyryl-CoA Product Beta-Ketophenylbutyryl-CoA
Reactant Info Product Info
Metabolic Enzyme Beta-Hydroxyacyl-CoA Dehydrogenase (HSDB) DME Info
Metabolic Type Unclear - Unclear
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005598 Phenylbutenoyl-CoA Beta-Hydroxyphenylbutyryl-CoA Unclear Sodium phenylbutyrate [1]
MR013768 Phenylbutenoyl-CoA Beta-Hydroxyphenylbutyryl-CoA Unclear - Unclear phenylbutyrate [2]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR005600 Beta-Ketophenylbutyryl-CoA Acetyl-CoA Unclear Sodium phenylbutyrate [1]
MR013771 Beta-Ketophenylbutyryl-CoA Acetyl-CoA Unclear - Unclear phenylbutyrate [2]
MR005601 Beta-Ketophenylbutyryl-CoA Phenylacetyl-CoA Unclear Sodium phenylbutyrate [1]
MR013770 Beta-Ketophenylbutyryl-CoA Phenylacetyl-CoA Unclear - Unclear phenylbutyrate [2]
References
1 Evidence for involvement of medium chain acyl-CoA dehydrogenase in the metabolism of phenylbutyrate
2 Phase 2 comparison of a novel ammonia scavenging agent with sodium phenylbutyrate in patients with urea cycle disorders: safety, pharmacokinetics and ammonia control

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