Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR014205)
Formula
ES
SVG example
Hydrolyzation
Reactant NUC?1031 Product Gemcitabine
Reactant Info Product Info
Metabolic Enzyme Esterases (ES) DME Info
Metabolic Type Hydrolysis - Hydrolyzation
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012143 Etirinotecan pegol Irinotecan Hydrolysis - Hydrolysis Etirinotecan pegol [1]
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR012146 Irinotecan APC,NPC Oxidation - Oxidation Etirinotecan pegol [1]
MR012144 Irinotecan SN-38 Unclear - Unclear Etirinotecan pegol [1]
References
1 Integrated population pharmacokinetics of etirinotecan pegol and its four metabolites in cancer patients with solid tumors

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