Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01462)
Xenobiotics Name
Rutecarpine
Xenobiotics Type
Natural Product(s), Extract(s) or Medicine(s)
Classification
Natural Product
Structure
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3D MOL 2D MOL
PubChem CID
65752
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Aminoglycoside phosphotransferase (aph-Ib) DME Info Campylobacter jejuni [1]
Cytochrome P450 1A2 (CYP1A2) DME Info Homo sapiens [2]
DME(s) Induced by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [3]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Cytochrome P450 1A2 (CYP1A2) DME Info IC50 = 0.022 microM [2]
References
1 Attenuation of adhesion, biofilm formation and quorum sensing of Campylobacter jejuni by Euodia ruticarpa. Phytother Res. 2016 Sep;30(9):1527-32.
2 Effect of structural modification on the inhibitory selectivity of rutaecarpine derivatives on human CYP1A1, CYP1A2, and CYP1B1. Bioorg Med Chem Lett. 2003 Aug 4;13(15):2535-8.
3 Beta-Carotene conversion into vitamin A in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 2005 Oct;46(10):3562-9.

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