Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO01485)
Xenobiotics Name
Thiostrepton
Xenobiotics Type
Pharmaceutical Agent(s)
Classification
Approved/Marketed Drug
Structure
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3D MOL 2D MOL
PubChem CID
16129638
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 1A1 (CYP1A1) DME Info Homo sapiens [1]
Cytochrome P450 2E1 (CYP2E1) DME Info Homo sapiens [1]
DME(s) Induced by This Xenobiotics
Glutathione reductase (GSR) DME Info Homo sapiens [2]
Prostaglandin G/H synthase 1 (COX-1) DME Info Homo sapiens [2]
Superoxide dismutase 1 (SOD1) DME Info Homo sapiens [2]
References
1 Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitors of aldosterone synthase. J Med Chem. 2005 Mar 10;48(5):1563-75.
2 Shotgun approach based comparative proteomic analysis of levo-tetrahydropalmatine-induced apoptosis in hepatocytes. Toxicol Lett. 2010 Apr 15;194(1-2):8-15.

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