General Information of Xenobiotics (ID: XEO03431)
Xenobiotics Name
Thanatin truncated isoform G18C(1-18)
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 102A1 (cyp102) DME Info Bacillus megaterium [1]
Cytochrome P450 MEG (cyp106) DME Info Bacillus megaterium [1]
Cytochrome P450 21A2 (cyp21) DME Info Bacillus megaterium [1]
Cytochrome P450 BM3 (cypBM3) DME Info Bacillus megaterium [1]
NADPH-dependent nitroreductase (nfrA1) DME Info Bacillus subtilis [1]
Glutamate racemase (MurI) DME Info Bacillus subtilis [1]
Glutamate racemase (MurI) DME Info Bacillus pumilus [1]
General stress protein 14 (ywrO) DME Info Bacillus subtilis [1]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Cytochrome P450 102A1 (cyp102) DME Info MIC = 5-10 microM [1]
Cytochrome P450 MEG (cyp106) DME Info MIC = 5-10 microM [1]
Cytochrome P450 21A2 (cyp21) DME Info MIC = 5-10 microM [1]
Cytochrome P450 BM3 (cypBM3) DME Info MIC = 5-10 microM [1]
NADPH-dependent nitroreductase (nfrA1) DME Info MIC = 5-10 microM [1]
Glutamate racemase (MurI) DME Info MIC = 5-10 microM [1]
Glutamate racemase (MurI) DME Info MIC = 5-10 microM [1]
General stress protein 14 (ywrO) DME Info MIC = 5-10 microM [1]
References
1 Structure-activity analysis of thanatin, a 21-residue inducible insect defense peptide with sequence homology to frog skin antimicrobial peptides. Proc Natl Acad Sci U S A. 1996 Feb 6;93(3):1221-5.

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