Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001042)
Formula Reactant Fingolimod Product Non-polar ceramides analogs of fingolimod
Reactant Info Product Info
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001041 Fingolimod (S)-enantiomer of fingolimod-phosphate Other reaction - Phosphorylation Fingolimod [1], [2]
MR001043 Fingolimod . Unclear Fingolimod [3]
MR001040 Fingolimod Fingolimod carboxylic acid metabolite Oxidation - Hydroxylation Fingolimod [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001047 Fingolimod hydrochloride Non-polar ceramides analogs of fingolimod Unclear Fingolimod hydrochloride [1]
References
1 Clinical pharmacokinetics of fingolimod Clin Pharmacokinet. 2012 Jan 1;51(1):15-28. doi: 10.2165/11596550-000000000-00000.
2 Ketoconazole increases fingolimod blood levels in a drug interaction via CYP4F2 inhibition J Clin Pharmacol. 2009 Feb;49(2):212-8. doi: 10.1177/0091270008329553.
3 LABEL:INGOLIMOD capsule

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