Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR001344)
Formula Reactant Ketoconazole epoxide intermediate Product Ketoconazole dihydroxyl intermediate
Reactant Info Product Info
Metabolic Type Other reaction - Hydration
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Produce The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001357 Ketoconazole Ketoconazole epoxide intermediate Unclear Ketoconazole [1]
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001345 Ketoconazole epoxide intermediate Ketoconazole ketone intermediate Oxidation - Oxidation Ketoconazole [1]
Other MR(s) Related to The Product of This MR
Other MR(s) That Metabolize The Produtc of This MR
MR ID Reactant Product MR Type Related Drug REF
MR001346 Ketoconazole dihydroxyl intermediate M3 (Ketoconazole) Oxidation - N-Dealkylation Ketoconazole [1]
MR001347 Ketoconazole dihydroxyl intermediate M5' (Ketoconazole) Oxidation - Oxidation Ketoconazole [1]
References
1 Revisiting the metabolism of ketoconazole using accurate mass Drug Metab Lett. 2009 Aug;3(3):191-8. doi: 10.2174/187231209789352085.

If you find any error in data or bug in web service, please kindly report it to Dr. Yin and Dr. Li.