Details of the Metabolic Reaction (MR)

General Information of This Metabolic Reaction (MR) (ID: MR007172)
Formula
SVG example
eta-hydroxylation
Reactant Amphetamine Product Norephedrine Norpxudoephed rine
Reactant Info Product Info
Metabolic Type Oxidation - eta-hydroxylation
Other MR(s) Related to The Reactant of This MR
Other MR(s) That Metabolize The Reactant of This MR
MR ID Reactant Product MR Type Related Drug REF
MR000220 Amphetamine 4-hydroxyamphetamine Oxidation - Hydroxylation Amphetamine [1]
MR000222 Amphetamine Norephedrine Oxidation - Hydroxylation Amphetamine [1]
MR000221 Amphetamine Phenylacetone Oxidation - Oxidative Deamination Amphetamine [1]
MR009989 Amphetamine 4-Hydroxyamphetamine Unclear - Unclear Metamfetamine [2]
MR010005 Amphetamine 4-Hydroxyamphetamine Unclear - Unclear Methamphetamine hydrochloride [2]
MR009985 Amphetamine Metamfetamine Metabolite M5 Unclear - Unclear Metamfetamine [2]
MR010001 Amphetamine Metamfetamine Metabolite M5 Unclear - Unclear Methamphetamine hydrochloride [2]
MR009987 Amphetamine Norephedrine Unclear - Unclear Metamfetamine [2]
MR010003 Amphetamine Norephedrine Unclear - Unclear Methamphetamine hydrochloride [2]
MR007171 Amphetamine p-Hydroxyamphetamine Oxidation - p-hydroxylation Famprofazone [3]
Other MR(s) Related to The Product of This MR
Other MR(s) That Produce The Product of This MR
MR ID Reactant Product MR Type Related Drug REF
MR007176 Ephedrine Pseudoephedrine Norephedrine Norpxudoephed rine Oxidation - N-demethylation Famprofazone [3]
References
1 Cytochromes P450: a structure-based summary of biotransformations using representative substrates Drug Metab Rev. 2008;40(1):1-100. doi: 10.1080/03602530802309742.
2 Metabolism of ( 14 C)methamphetamine in man, the guinea pig and the rat
3 Identification of new urinary metabolites of famprofazone in humans

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