Detail Information of Xenobiotics

General Information of Xenobiotics (ID: XEO02521)
Xenobiotics Name
Brevinin-1E
Xenobiotics Type
Amino Acid(s), Peptide(s) or Protein(s)
Classification
Peptide
DME(s) Modulated by This Xenobiotics
DME(s) Inhibited by This Xenobiotics
Cytochrome P450 102A1 (cyp102) DME Info Bacillus megaterium [1], [2]
Cytochrome P450 MEG (cyp106) DME Info Bacillus megaterium [1], [2]
Cytochrome P450 21A2 (cyp21) DME Info Bacillus megaterium [1], [2]
Cytochrome P450 BM3 (cypBM3) DME Info Bacillus megaterium [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info Pseudomonas aeruginosa [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info Pseudomonas aeruginosa [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info Staphylococcus aureus [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info Pseudomonas aeruginosa [1], [2]
Xenobiotics-DME Activity Data
Xenobiotics-DME Activity Data Cytochrome P450 102A1 (cyp102) DME Info MIC = 0.4 microM [1], [2]
Cytochrome P450 MEG (cyp106) DME Info MIC = 0.4 microM [1], [2]
Cytochrome P450 21A2 (cyp21) DME Info MIC = 0.4 microM [1], [2]
Cytochrome P450 BM3 (cypBM3) DME Info MIC = 0.4 microM [1], [2]
D-Lactate dehydrogenase (ldhA) DME Info MIC = 30.6 microM [1], [2]
Arylamine N-acetyltransferase (NAT) DME Info MIC = 30.6 microM [1], [2]
NADPH-dependent oxidoreductase (nfrA) DME Info MIC = 0.6 microM [1], [2]
Hydroxybenzoate 3-monooxygenase (pobA) DME Info MIC = 30.6 microM [1], [2]
References
1 Novel antimicrobial peptides from skin secretion of the European frog Rana esculenta. FEBS Lett. 1993 Jun 14;324(2):159-61.
2 Antimicrobial peptides from skin secretions of Rana esculentaMolecular cloning of cDNAs encoding esculentin and brevinins and isolation of new active peptides. J Biol Chem. 1994 Apr 22;269(16):11956-61.

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